The Scientist

June 2008

Features:

• Before Darwin coVer storY » Evolution’s real problem, eRic
• Diverting a Diet Drug Recently, GlaxoSmithKline convinced Roche to sell its controversial obesity drug, and then con- vinced the US Food and Drug Administration to let GSK sell the drug over-the-counter, without a prescription. FRAn
• Best Places to Work: Industry The competitive world of industry fosters an appetite to get ahead. In our sixth annual survey, eLie
• editorial From Me to We The Scientist Community is about to take off. We hope you’ll join us. BY
• notebooks Agenda, cave crawler, the worm hunter, Finding the false, Inducing autism, Unlocking the clock
• BioBusiness Win, Place, or cell Can a company harness stem cells to treat injured horses? BY
• careers the Industry Roads Less taken Four high-paying, in-demand, industry jobs scientists often over- look, and tips on how to get in. BY
• opinion Academic Medicine to the Rescue? Full partnerships with industry are spawning a new era of translational medicine. BY
• column Why national Laboratories? For certain experiments, I’ve learned that there’s no better place to do biology. BY
• Proile A Mind Apart Sean Eddy uses his decades of expe- rience playing video games to design software that found an entire new class of genes. And he’s still looking. BY
• the Literature Hot Papers: Clues to why pluripotent stem cells differentiate or remain pluripotent; evidence of widespread positive selection in the human genome; new modeling methods better predict species’ distributions. Citation Classic: Luc Montagnier and his colleagues describe the experi- ments proving that a retrovirus is the causative agent of AIDS. Scientist to Watch: Peter Reddien
• Lab tools shaping Up How to find your way around three- dimensional cell culture. BY
• Foundations C. elegans cell lineage, circa 1981 BY